Tissue Engineering | Technologies and Therapeutic Areas

Description
Table of Contents
Major Market Players

Despite being in existence for about two decades, the field of tissue engineering can still be assumed to be a developing discipline involving basic and applied multidisciplinary biomedical research. This subject utilization of the principles and methods employed in engineering and life sciences, which are then combined with clinical expertise with a focus on developing biological tissue substitutes that enable in restoring, maintaining or enhancing the function of diseased or damaged human tissues. Researchers from a wide range of disciplines have collaborated in fostering the development of a host of exceptional inventions, state-of-the-art research tools and scientific techniques that are finding diverse application in this as yet nascent area. While the initial clinically relevant efforts in tissue engineering were focused on generating bioengineered skin substitutes for severely burned patients, the past two decades have witnessed considerable evolution in this field, with the ideas and applications of these principles being employed for an extensive array of tissues and organs. Skin, cartilage, bone, blood vessels, pancreas, heart valves, breast, nerves, trachea, bowel, kidney, lung and liver comprise some of the distinctive instances of areas where tissue engineered substitutes have either been employed or are under investigation.

As can be expected with any emerging area of science, the initial years for tissue engineering were full of enthusiasm and offered the promise of significant achievements, which, though, were followed by periods of shortcomings when translated into clinical practice. The practical performance of the clinically implanted cultured tissue surrogates fell far short of expectations and threw up a number of challenges. Despite this, endeavors remained focused on further enhancements and led to the development of innovative solutions for overcoming these problems. For instance, new alternatives for cell and tissue delivery were created even in the apparently simple process of tissue engineering substitutes, such as epithelial sheet grafts without necessary three-dimensional vascular (micro) networks by comprehending that in place of transplanting readymade multilayer epithelial sheets, delivering single cell as a suspension in a biological carrier offered better performance and ease of handling.

The knowledge obtained from tissue engineering experiments has found application in a range of medical therapies, such as direct organ or tissue replacement. Studies on material interactions under laboratory conditions have resulted in improving medical devices. For example, the modification of vascular stents has led to their performing better in humans, thereby contributing to a growing number of procedures associated with atherosclerosis or coronary artery disease. The seeding of cells onto tubular biopolymer scaffolds has resulted in generating vascular grafts with the help of smooth muscle cells and an inner lining produced by endothelial cells, constituting one instance capable of addressing huge clinical needs in the future.

Worldwide market for Tissue Engineering technologies explored in this study includes Cell Culture, Immunomodulation and Stem Cell. The report also focuses on therapeutic applications of tissue engineering comprising Cardiovascular, Dental/Oral Neurological, Oncology, Orthopedic, Skin/Integumentary and Others. The markets for the above mentioned technologies and therapeutic applications are analyzed in terms of USD. Global market for Tissue Engineering, estimated at US$23 billion in 2015, forecast to reach US$27.3 billion in 2015, and is further expected to register a CAGR of about 23% between 2016 and 2022 to touch a projected US$94.2 billion by 2022.

The study review, analyze and projects the tissue engineering market for global and the regional markets including North America, Europe, Asia-Pacific and Rest of World. The regional markets further analyzed for 5 independent countries across North America – The United States and Canada; and Europe – France, Germany and the United Kingdom.

This 279 pages market research report includes 113 charts (includes a data table and graphical representation for each chart), supported with meaningful and easy to understand graphical presentation, of market numbers. The report profiles 31 key global players and 39 major players across North America – 28; Europe – 7; Asia-Pacific – 3; and Rest of World – 1. The research also provides the listing of the companies engaged in research and development and services of tissue engineering. The global list of companies covers addresses, contact numbers and the website addresses of 300 companies.

PART A: GLOBAL MARKET PERSPECTIVE

1. INTRODUCTION
1.1 Product Outline
1.1.1 Biomaterials
1.1.2 Cells
1.1.3 Biomolecules
1.1.4 Aspects of Engineering Design
1.1.5 Biomechanical Design Aspects
1.1.6 Informatics to Support Tissue Engineering
1.1.7 Stem Cell Research
1.1.8 Tissue Engineering Technologies
1.1.8.1 Cell Culture
1.1.8.1.1 Applications of Cell Culture
1.1.8.1.2 Cell Culture in Tissue Engineering
1.1.8.2 Immunomodulation
1.1.8.2.1 Immunomodulatory Effect of Mesenchymal Stem Cells in Tissue Engineering
1.1.8.3 Stem Cell
1.1.8.3.1 Categories of Stem Cells
1.1.8.3.2 Scaffolds
1.1.8.3.3 Stem Cell Technology in Tissue Engineering
1.1.8.3.3.1 Bone Tissue Engineering
1.1.8.3.3.2 Cardiac Tissue Engineering
1.1.8.3.3.3 Liver Tissue Engineering
1.1.8.3.3.4 Neural Tissue Engineering
1.1.8.3.3.5 Other Applications
1.1.9 Therapeutic Applications of Tissue Engineering and Regenerative Medicine
1.1.9.1 Cardiovascular Applications
1.1.9.1.1 Cardiac Tissue Engineering: An Overview
1.1.9.1.2 Identification of Basic Cell Responses
1.1.9.1.3 3-Dimensional Tissue Engineering
1.1.9.1.4 Further 3-D Approaches and Considerations
1.1.9.1.5 Cardiovascular Tissue Engineering and Bioreactor Technology
1.1.9.1.6 Limiting Cells or Materials
1.1.9.2 Dental/Oral Applications
1.1.9.2.1 Dental Tissue Regeneration through Tissue Engineering Strategy
1.1.9.2.2 Harvesting Teeth Created by Tissue Engineering
1.1.9.2.3 Research Goals Currently Targeted
1.1.9.2.4 Process of Tissue Engineering for Tooth Replacement: What Future Trends Indicate
1.1.9.3 Neurology Applications
1.1.9.3.1 Neural Tissue Engineering or Neuroregeneration
1.1.9.3.2 Biomaterial Scaffold Development for Nerve Tissue Engineering: Biomaterial Mediated Neural Regeneration
1.1.9.4 Oncology Applications
1.1.9.4.1 Cancer
1.1.9.4.2 Cancer Biology from Tissue Engineering?s Perspective
1.1.9.4.3 Tissue Engineering Technology Platforms? Translation into Cancer Research
1.1.9.5 Orthopedic Applications
1.1.9.5.1 Bone Regeneration Using Orthopedic Tissue Engineering
1.1.9.5.2 Articular Cartilage Degeneration and Osteoarthritis, Repair, Regeneration and Transplantation
1.1.9.6 Skin/Integumentary Applications
1.1.9.6.1 Burns
1.1.9.6.2 Diabetic Ulcers
1.1.9.6.3 Venous Ulcers
1.1.9.6.4 Plastic and Reconstructive Surgery
1.1.9.7 Other Applications
1.1.9.7.1 Autoimmune Disorders
1.1.9.7.2 Ophthalmology
1.1.9.7.3 Organ Replacement/Transplant
1.1.9.7.4 Urology

2. KEY MARKET TRENDS
2.1 Tissue Engineering Enters the ?4D? Age
2.2 Cartilage Restoration Gets a Boost with Novel Tissue Engineering Approach
2.3 3-D Designs for Neural Tissue Engineering Witnesses Advancements
2.4 Peripheral Nerve Injuries Repaired Using Tissue Engineering
2.5 Biosensor Application in Tissue Engineering Gaining Prominence
2.6 Protein Mimic Offers Potential as Glue in Tissue Engineering
2.7 3D-Printed Biopolymers in Tissue Engineering Applications
2.8 Novel Tissue Scaffold Technology Shows Promise in Rebuilding Large Organs
2.9 Co-Cultures Based on Stem Cells Foster Progression in Tissue Engineering
2.10 Rapid Growth in Use of Collagen-Based Biomaterials for Tissue Engineering Applications
2.11 Tissue Engineering Gaining Ground in Corneal Stem Cell-Based Therapies
2.12 Tissue Engineering for Blood Vessels Making Steady Progress
2.13 Tissue Engineering Helps in Growing Leg Muscle from Cells in a Dish
2.14 Advancements in 3D Printing and Tissue Engineering Technology
2.15 Click Chemistry Finds Application in Tissue Engineering

3. KEY GLOBAL PLAYERS

4. KEY BUSINESS TRENDS
Japanese PMDA Approved an Expanded Indication for CryoLife‘s BioGlue
Caladrius Biosciences is the New Corporate Name of NeoStem
USPTO Issued a New Patent for Ocata‘s RPE Therapy to Treat Macular Degenerative Diseases
Acelity L.P. Inc. formed Distribution Pact with Joerns RecoverCare
Use of ESI‘s Clinical-Grade hES Cells in Preclinical Research to Treat Huntington‘s disease
EMA Slated ATMP Classification for NBS20, NeoStem‘s Lead Immuno-oncology Product Candidate
BioTime‘s ESI and BRICOH Sign a Selective License Agreement
Display of Early Clinical Data Exhibiting the Competence of PanC-Dx™ at AACR 2015 Annual Meeting
Celgene and Mesoblast Ink Collaborative Agreement
Japan Patent Office Issued New Patent to ISCO
Athersys Marked MultiStem® Cell Therapy Development and Commercialization Pact with Chugai
Issuance of Two New US Patents for Ocata‘s HMC Technology
ESI BIO and Pivotal Scientific Ltd form Stem Cell Products Distribution Pact
ESI BIO and 2B Scientific Partnered to Distribute Stem Cell Products in the UK and Ireland
Osiris and Stryker Inked Collaboration to Develop and Commercialize BIO4™
Ocata Therapeutics is the New Name of Advanced Cell Technology
Osiris Established Strategic Alliance with Arthrex to Develop and Commercialize Cartiform®
Acelity is the New Name of Centaur Guernsey
Advanced Cell Technology Received US Patent Extending the Making Process of Renewable Stem Cell Source-based Dendritic Cells
CorCell Released Novel Service Offering to Differentiate and Expand Mesenchymal Stem Cells
REDDSTAR Project Utilized Excellagen® flowable dermal matrix and Cyndacel-M™ mesenchymal stromal stem cell therapy
Advanced Cell Technology Detected a Novel Process to Yield Effective MSCs from Pluripotent Stem Cells
Advanced Adipose Tissue Injector for Enhanced Fat Grafting Procedures Acquired by LifeCell
Organogenesis Takeover Shire‘s Dermagraft® Assets
Japan Patent Office Issued Novel Patents for Athersys‘ Cell Therapy Technology
European Medicines Agency Grants Orphan Drug Designation for MultiStem® Therapy of Athersys
Tissue Regenix Mark Seven Individual Regional Sales Distribution Deals in the US
New TTF-iPS Technology Developed by International Stem Cell Corporation
Consolidation of BioTime‘s Research Products Business into a New ESI BIO Division
Systagenix Acquired by KCI
Cardium Joined Forces with Boston Children‘s Hospital Researchers
Launch of REVOLVE™ System by LifeCell
ViaCyte Received Funds from JDRF and CIRM to Develop a New Stem Cell Therapy

5. GLOBAL MARKET OVERVIEW
5.1 Global Tissue Engineering Market Overview by Technology
5.1.1 Global Tissue Engineering Technology Overview by Geographic Region
5.1.1.1 Cell Culture
5.1.1.2 Immunomodulation
5.1.1.3 Stem Cell
5.2 Global Tissue Engineering Market Overview by Application
5.2.1 Global Tissue Engineering Application Overview by Geographic Region
5.2.1.1 Cardiovascular
5.2.1.2 Dental/Oral
5.2.1.3 Neurological
5.2.1.4 Oncology
5.2.1.5 Orthopedic
5.2.1.6 Skin/Integumentary
5.2.1.7 Other Applications

PART B: REGIONAL MARKET PERSPECTIVE

REGIONAL MARKET OVERVIEW

1. NORTH AMERICA
1.1 North American Tissue Engineering Market Overview by Region
1.2 North American Tissue Engineering Market Overview by Technology
1.2.1 North American Tissue Engineering Technology Overview by Region
1.2.1.1 Cell Culture
1.2.1.2 Immunomodulation
1.2.1.3 Stem Cell
1.3 North American Tissue Engineering Market Overview by Application
1.3.1 North American Tissue Engineering Application Overview by Region
1.3.1.1 Cardiovascular
1.3.1.2 Dental/Oral
1.3.1.3 Neurological
1.3.1.4 Oncology
1.3.1.5 Orthopedic
1.3.1.6 Skin/Integumentary
1.3.1.7 Other Applications
1.4 Major Market Players
Acelity L.P. Inc. (United States)
Kinetic Concepts, Inc (United States)
LifeCell Corporation (United States)
Acell Inc. (United States)
Athersys, Inc. (United States)
Biotime, Inc. (United States)
Asterias Biotherapeutics, Inc. (United States)
ESI BIO (United States)
OncoCyte Corporation (United States)
C. R. Bard, Inc. (United States)
Caladrius Biosciences, Inc. (United States)
Cellerant Therapeutics, Inc. (United States)
Cryolife Inc. (United States)
Cytograft Tissue Engineering, Inc. (United States)
Cytori Therapeutics, Inc. (United States)
Histogenics Corporation (United States)
Integra Lifesciences Holdings Corporation (United States)
International Stem Cell Corporation (United States)
Lifeline Cell Technology LLC (United States)
Kensey Nash Corporation (United States)
Ocata Therapeutics, Inc (United States)
Organogenesis Inc. (United States)
Osiris Therapeutics, Inc. (United States)
RTI Surgical, Inc. (United States)
Stemcell Technologies Inc. (Canada)
Taxus Cardium Pharmaceuticals Group, Inc. (United States)
Viacyte, Inc. (United States)
Zimmer Biomet Holdings Inc. (United States)

1.5 North American Tissue Engineering Market Overview by Country
1.5.1 The United States
1.5.1.1 Market Overview by Technology
1.5.1.2 Market Overview by Application

1.5.2 Canada
1.5.2.1 Market Overview by Technology
1.5.2.2 Market Overview by Application

2. EUROPE
2.1 European Tissue Engineering Market Overview by Region
2.2 European Tissue Engineering Market Overview by Technology
2.2.1 European Tissue Engineering Technology Overview by Geographic Region
2.2.1.1 Cell Culture
2.2.1.2 Immunomodulation
2.2.1.3 Stem Cell
2.3 European Tissue Engineering Market Overview by Application
2.3.1 European Tissue Engineering Application Overview by Geographic Region
2.3.1.1 Cardiovascular
2.3.1.2 Dental/Oral
2.3.1.3 Neurological
2.3.1.4 Oncology
2.3.1.5 Orthopedic
2.3.1.6 Skin/Integumentary
2.3.1.7 Other Applications
2.4 Major Market Players
Biocomposites Ltd. (United Kingdom)
Biotissue Technologies GmbH (Germany)
Episkin (France)
Koninklijke DSM NV (The Netherlands)
Systagenix Wound Management Limited (United Kingdom)
TETEC® Tissue Engineering Technologies AG (Germany)
Tissue Regenix Group PLC (United Kingdom)

2.5 European Tissue Engineering Market Overview by Country
2.5.1 France
2.5.1.1 Market Overview by Technology
2.5.1.2 Market Overview by Application

2.5.2 Germany
2.5.2.1 Market Overview by Technology
2.5.2.2 Market Overview by Application

2.5.3 The United Kingdom
2.5.3.1 Market Overview by Technology
2.5.3.2 Market Overview by Application

2.5.4 Rest of Europe
2.5.4.1 Market Overview by Technology
2.5.4.2 Market Overview by Application

3. ASIA-PACIFIC
3.1 Asia-Pacific Tissue Engineering Market Overview by Technology
3.2 Asia-Pacific Tissue Engineering Market Overview by Application
3.3 Major Market Players
Japan Tissue Engineering Co Ltd (Japan)
Lifecord International Co Ltd (South Korea)
Piramal Enterprises Limited (India)

4. REST OF WORLD
4.1 Rest of World Tissue Engineering Market Overview by Technology
4.2 Rest of World Tissue Engineering Market Overview by Application
4.3 Major Market Player
Gamida Cell Ltd. (Israel)

PART C: GUIDE TO THE INDUSTRY
1. NORTH AMERICA
2. EUROPE
3. ASIA-PACIFIC
4. REST OF WORLD

PART D: ANNEXURE
1. RESEARCH METHODOLOGY
2. FEEDBACK

Charts & Graphs

PART A: GLOBAL MARKET PERSPECTIVE
Chart 1: Global Tissue Engineering Market Analysis (2012-2022) in USD Million
Chart 2: Global Tissue Engineering Market Analysis (2012-2022) by Technology – Cell Culture, Immunomodulation and Stem Cell in USD Million
Chart 3: Glance at 2012, 2017 and 2022 Global Tissue Engineering Market Share (%) by Technology – Cell Culture, Immunomodulation and Stem Cell
Chart 4: Global Cell Culture Tissue Engineering Market Analysis (2012-2022) by Region – North America, Europe, Asia-Pacific and Rest of World in USD Million
Chart 5: Glance at 2012, 2017 and 2022 Global Cell Culture Tissue Engineering Market Share (%) by Region – North America, Europe, Asia-Pacific and Rest of World
Chart 6: Global Immunomodulation Tissue Engineering Market Analysis (2012-2022) by Region – North America, Europe, Asia-Pacific and Rest of World in USD Million
Chart 7: Glance at 2012, 2017 and 2022 Global Immunomodulation Tissue Engineering Market Share (%) by Region – North America, Europe, Asia-Pacific and Rest of World
Chart 8: Global Stem Cell Tissue Engineering Market Analysis (2012-2022) by Region – North America, Europe, Asia-Pacific and Rest of World in USD Million
Chart 9: Glance at 2012, 2017 and 2022 Global Stem Cell Tissue Engineering Market Share (%) by Region – North America, Europe, Asia-Pacific and Rest of World
Chart 10: Global Tissue Engineering Market (2010-2020) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications in USD Million
Chart 11: Glance at 2012, 2017 and 2022 Global Tissue Engineering Market Share (%) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications
Chart 12: Global Tissue Engineering Market Analysis (2012-2022) in Cardiovascular Applications by Region – North America, Europe, Asia-Pacific and Rest of World in USD Million
Chart 13: Glance at 2012, 2017 and 2022 Global Tissue Engineering Market Share (%) in Cardiovascular Applications by Region – North America, Europe, Asia-Pacific and Rest of World
Chart 14: Global Tissue Engineering Market Analysis (2012-2022) in Dental/Oral Applications by Region – North America, Europe, Asia-Pacific and Rest of World in USD Million
Chart 15: Glance at 2012, 2017 and 2022 Global Tissue Engineering Market Share (%) in Dental/Oral Applications by Region – North America, Europe, Asia-Pacific and Rest of World
Chart 16: Global Tissue Engineering Market Analysis (2012-2022) in Neurological Applications by Region – North America, Europe, Asia-Pacific and Rest of World in USD Million
Chart 17: Glance at 2012, 2017 and 2022 Global Tissue Engineering Market Share (%) in Neurological Applications by Region – North America, Europe, Asia-Pacific and Rest of World
Chart 18: Global Tissue Engineering Market Analysis (2012-2022) in Oncology Applications by Region – North America, Europe, Asia-Pacific and Rest of World in USD Million
Chart 19: Glance at 2012, 2017 and 2022 Global Tissue Engineering Market Share (%) in Oncology Applications by Region – North America, Europe, Asia-Pacific and Rest of World
Chart 20: Global Tissue Engineering Market Analysis (2012-2022) in Orthopedic Applications by Region – North America, Europe, Asia-Pacific and Rest of World in USD Million
Chart 21: Glance at 2012, 2017 and 2022 Global Tissue Engineering Market Share (%) in Orthopedic Applications by Region – North America, Europe, Asia-Pacific and Rest of World
Chart 22: Global Tissue Engineering Market Analysis (2012-2022) in Skin/Integumentary Applications by Region – North America, Europe, Asia-Pacific and Rest of World in USD Million
Chart 23: Glance at 2012, 2017 and 2022 Global Tissue Engineering Market Share (%) in Skin/Integumentary Applications by Region – North America, Europe, Asia-Pacific and Rest of World
Chart 24: Global Tissue Engineering Market Analysis (2012-2022) in Other Applications by Region – North America, Europe, Asia-Pacific and Rest of World in USD Million
Chart 25: Glance at 2012, 2017 and 2022 Global Tissue Engineering Market Share (%) in Other Applications by Region – North America, Europe, Asia-Pacific and Rest of World

PART B: REGIONAL MARKET PERSPECTIVE
Chart 26: Global Tissue Engineering Market Analysis (2012-2022) by Region – North America, Europe, Asia-Pacific and Rest of World in USD Million
Chart 27: Glance at 2012, 2017 and 2022 Global Tissue Engineering Market Share (%) by Region – North America, Europe, Asia-Pacific and Rest of World

NORTH AMERICA
Chart 28: North American Tissue Engineering Market Analysis (2012-2022) in USD Million
Chart 29: North American Tissue Engineering Market Analysis (2012-2022) by Region – United States and Canada in USD Million
Chart 30: Glance at 2012, 2017 and 2022 North American Tissue Engineering Market Share (%) by Region – United States and Canada
Chart 31: North American Tissue Engineering Market Analysis (2012-2022) by Technology – Cell Culture, Immunomodulation and Stem Cell in USD Million
Chart 32: Glance at 2012, 2017 and 2022 North American Tissue Engineering Market Share (%) by Technology – Cell Culture, Immunomodulation and Stem Cell
Chart 33: North American Cell Culture Tissue Engineering Market Analysis (2012-2022) by Region – United States and Canada in USD Million
Chart 34: Glance at 2012, 2017 and 2022 North American Cell Culture Tissue Engineering Market Share (%) by Region – United States and Canada
Chart 35: North American Immunomodulation Tissue Engineering Market Analysis (2012-2022) by Region – United States and Canada in USD Million
Chart 36: Glance at 2012, 2017 and 2022 North American Immunomodulation Tissue Engineering Market Share (%) by Region – United States and Canada
Chart 37: North American Stem Cell Tissue Engineering Market Analysis (2012-2022) by Region – United States and Canada in USD Million
Chart 38: Glance at 2012, 2017 and 2022 North American Stem Cell Tissue Engineering Market Share (%) by Region – United States and Canada
Chart 39: North American Tissue Engineering Market Analysis (2012-2022) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications in USD Million
Chart 40: Glance at 2012, 2017 and 2022 North American Tissue Engineering Market Share (%) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications
Chart 41: North American Tissue Engineering Market Analysis (2012-2022) in Cardiovascular Applications by Region – United States and Canada in USD Million
Chart 42: Glance at 2012, 2017 and 2022 North American Tissue Engineering Market Share (%) in Cardiovascular Applications by Region – United States and Canada
Chart 43: North American Tissue Engineering Market Analysis (2012-2022) in Dental/Oral Applications by Region – United States and Canada in USD Million
Chart 44: Glance at 2012, 2017 and 2022 North American Tissue Engineering Market Share (%) in Dental/Oral Applications by Region – United States and Canada
Chart 45: North American Tissue Engineering Market Analysis (2012-2022) in Neurological Applications by Region – United States and Canada in USD Million
Chart 46: Glance at 2012, 2017 and 2022 North American Tissue Engineering Market Share (%) in Neurological Applications by Region – United States and Canada
Chart 47: North American Tissue Engineering Market Analysis (2012-2022) in Oncology Applications by Region – United States and Canada in USD Million
Chart 48: Glance at 2012, 2017 and 2022 North American Tissue Engineering Market Share (%) in Oncology Applications by Region – United States and Canada
Chart 49: North American Tissue Engineering Market Analysis (2012-2022) in Orthopedic Applications by Region – United States and Canada in USD Million
Chart 50: Glance at 2012, 2017 and 2022 North American Tissue Engineering Market Share (%) in Orthopedic Applications by Region – United States and Canada
Chart 51: North American Tissue Engineering Market Analysis (2012-2022) in Skin/Integumentary Applications by Region – United States and Canada in USD Million
Chart 52: Glance at 2012, 2017 and 2022 North American Tissue Engineering Market Share (%) in Skin/Integumentary Applications by Region – United States and Canada
Chart 53: North American Tissue Engineering Market Analysis (2012-2022) in Other Applications by Region – United States and Canada in USD Million
Chart 54: Glance at 2012, 2017 and 2022 North American Tissue Engineering Market Share (%) in Other Applications by Region – United States and Canada

The United States
Chart 55: United States Tissue Engineering Market Analysis (2012-2022) by Technology – Cell Culture, Immunomodulation and Stem Cell in USD Million
Chart 56: Glance at 2012, 2017 and 2022 United States Tissue Engineering Market Share (%) by Technology – Cell Culture, Immunomodulation and Stem Cell
Chart 57: United States Tissue Engineering Market Analysis (2012-2022) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications in USD Million
Chart 58: Glance at 2012, 2017 and 2022 United States Tissue Engineering Market Share (%) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications

Canada
Chart 59: Canadian Tissue Engineering Market Analysis (2012-2022) by Technology – Cell Culture, Immunomodulation and Stem Cell in USD Million
Chart 60: Glance at 2012, 2017 and 2022 Canadian Tissue Engineering Market Share (%) by Technology – Cell Culture, Immunomodulation and Stem Cell
Chart 61: Canadian Tissue Engineering Market Analysis (2012-2022) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications in USD Million
Chart 62: Glance at 2012, 2017 and 2022 Canadian Tissue Engineering Market Share (%) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications

EUROPE
Chart 63: European Tissue Engineering Market Analysis (2012-2022) in USD Million
Chart 64: European Tissue Engineering Market Analysis (2012-2022) by Region – France, Germany, United Kingdom and Rest of Europe in USD Million
Chart 65: Glance at 2012, 2017 and 2022 European Tissue Engineering Market Share (%) by Region – France, Germany, United Kingdom and Rest of Europe
Chart 66: European Tissue Engineering Market Analysis (2012-2022) by Technology – Cell Culture, Immunomodulation and Stem Cell in USD Million
Chart 67: Glance at 2012, 2017 and 2022 European Tissue Engineering Market Share (%) by Technology – Cell Culture, Immunomodulation and Stem Cell
Chart 68: European Cell Culture Tissue Engineering Market Analysis (2012-2022) by Region – France, Germany, United Kingdom and Rest of Europe in USD Million
Chart 69: Glance at 2012, 2017 and 2022 European Cell Culture Tissue Engineering Market Share (%) by Region – France, Germany, United Kingdom and Rest of Europe
Chart 70: European Immunomodulation Tissue Engineering Market Analysis (2012-2022) by Region – France, Germany, United Kingdom and Rest of Europe in USD Million
Chart 71: Glance at 2012, 2017 and 2022 European Immunomodulation Tissue Engineering Market Share (%) by Region – France, Germany, United Kingdom and Rest of Europe
Chart 72: European Stem Cell Tissue Engineering Market Analysis (2012-2022) by Region – France, Germany, United Kingdom and Rest of Europe in USD Million
Chart 73: Glance at 2012, 2017 and 2022 European Stem Cell Tissue Engineering Market Share (%) by Region – France, Germany, United Kingdom and Rest of Europe
Chart 74: European Tissue Engineering Market Analysis (2012-2022) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications in USD Million
Chart 75: Glance at 2012, 2017 and 2022 European Tissue Engineering Market Share (%) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications
Chart 76: European Tissue Engineering Market Analysis (2012-2022) in Cardiovascular Applications by Region – France, Germany, United Kingdom and Rest of Europe in USD Million
Chart 77: Glance at 2012, 2017 and 2022 European Tissue Engineering Market Share (%) in Cardiovascular Applications by Region – France, Germany, United Kingdom and Rest of Europe
Chart 78: European Tissue Engineering Market Analysis (2012-2022) in Dental/Oral Applications by Region – France, Germany, United Kingdom and Rest of Europe in USD Million
Chart 79: Glance at 2012, 2017 and 2022 European Tissue Engineering Market Share (%) in Dental/Oral Applications by Region – France, Germany, United Kingdom and Rest of Europe
Chart 80: European Tissue Engineering Market Analysis (2012-2022) in Neurological Applications by Region – France, Germany, United Kingdom and Rest of Europe in USD Million
Chart 81: Glance at 2012, 2017 and 2022 European Tissue Engineering Market Share (%) in Neurological Applications by Region – France, Germany, United Kingdom and Rest of Europe
Chart 82: European Tissue Engineering Market Analysis (2012-2022) in Oncology Applications by Region – France, Germany, United Kingdom and Rest of Europe in USD Million
Chart 83: Glance at 2012, 2017 and 2022 European Tissue Engineering Market Share (%) in Oncology Applications by Region – France, Germany, United Kingdom and Rest of Europe
Chart 84: European Tissue Engineering Market Analysis (2012-2022) in Orthopedic Applications by Region – France, Germany, United Kingdom and Rest of Europe in USD Million
Chart 85: Glance at 2012, 2017 and 2022 European Tissue Engineering Market Share (%) in Orthopedic Applications by Region – France, Germany, United Kingdom and Rest of Europe
Chart 86: European Tissue Engineering Market Analysis (2012-2022) in Skin/Integumentary Applications by Region – France, Germany, United Kingdom and Rest of Europe in USD Million
Chart 87: Glance at 2012, 2017 and 2022 European Tissue Engineering Market Share (%) in Skin/Integumentary Applications by Region – France, Germany, United Kingdom and Rest of Europe
Chart 88: European Tissue Engineering Market Analysis (2012-2022) in Other Applications by Region – France, Germany, United Kingdom and Rest of Europe in USD Million
Chart 89: Glance at 2012, 2017 and 2022 European Tissue Engineering Market Share (%) in Other Applications by Region – France, Germany, United Kingdom and Rest of Europe

France
Chart 90: French Tissue Engineering Market Analysis (2012-2022) by Technology – Cell Culture, Immunomodulation and Stem Cell in USD Million
Chart 91: Glance at 2012, 2017 and 2022 French Tissue Engineering Market Share (%) by Technology – Cell Culture, Immunomodulation and Stem Cell
Chart 92: French Tissue Engineering Market Analysis (2012-2022) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications in USD Million
Chart 93: Glance at 2012, 2017 and 2022 French Tissue Engineering Market Share (%) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications

Germany
Chart 94: German Tissue Engineering Market Analysis (2012-2022) by Technology – Cell Culture, Immunomodulation and Stem Cell in USD Million
Chart 95: Glance at 2012, 2017 and 2022 German Tissue Engineering Market Share (%) by Technology – Cell Culture, Immunomodulation and Stem Cell
Chart 96: German Tissue Engineering Market Analysis (2012-2022) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications in USD Million
Chart 97: Glance at 2012, 2017 and 2022 German Tissue Engineering Market Share (%) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications

The United Kingdom
Chart 98: United Kingdom Tissue Engineering Market Analysis (2012-2022) by Technology – Cell Culture, Immunomodulation and Stem Cell in USD Million
Chart 99: Glance at 2012, 2017 and 2022 United Kingdom Tissue Engineering Market Share (%) by Technology – Cell Culture, Immunomodulation and Stem Cell
Chart 100: United Kingdom Tissue Engineering Market Analysis (2012-2022) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications in USD Million
Chart 101: Glance at 2012, 2017 and 2022 United Kingdom Tissue Engineering Market Share (%) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications

Rest of Europe
Chart 102: Rest of Europe Tissue Engineering Market Analysis (2012-2022) by Technology – Cell Culture, Immunomodulation and Stem Cell in USD Million
Chart 103: Glance at 2012, 2017 and 2022 Rest of Europe Tissue Engineering Market Share (%) by Technology – Cell Culture, Immunomodulation and Stem Cell
Chart 104: Rest of Europe Tissue Engineering Market Analysis (2012-2022) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications in USD Million
Chart 105: Glance at 2012, 2017 and 2022 Rest of Europe Tissue Engineering Market Share (%) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications

ASIA-PACIFIC
Chart 106: Asia-Pacific Tissue Engineering Market Analysis (2012-2022) by Technology – Cell Culture, Immunomodulation and Stem Cell in USD Million
Chart 107: Glance at 2012, 2017 and 2022 Asia-Pacific Tissue Engineering Market Share (%) by Technology – Cell Culture, Immunomodulation and Stem Cell
Chart 108: Asia-Pacific Tissue Engineering Market Analysis (2012-2022) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications in USD Million
Chart 109: Glance at 2012, 2017 and 2022 Asia-Pacific Tissue Engineering Market Share (%) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications

REST OF WORLD
Chart 110: Rest of World Tissue Engineering Market Analysis (2012-2022) by Technology – Cell Culture, Immunomodulation and Stem Cell in USD Million
Chart 111: Glance at 2012, 2017 and 2022 Rest of World Tissue Engineering Market Share (%) by Technology – Cell Culture, Immunomodulation and Stem Cell
Chart 112: Rest of World Tissue Engineering Market Analysis (2012-2022) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications in USD Million
Chart 113: Glance at 2012, 2017 and 2022 Rest of World Tissue Engineering Market Share (%) by Application – Cardiovascular, Dental/Oral, Neurological, Oncology, Orthopedic, Skin/Integumentary and Other Applications

Tables:
Table 1: Scaffold Biomaterials and Stem Cells Currently Used in Tissue Engineering
Table 2: The Positives and Negatives of Prominent Approaches to Cardiac Tissue Engineering

Acelity L.P. Inc.
Acell Inc.
Athersys, Inc.
Biocomposites Ltd.
Biotime, Inc.
Biotissue Technologies GmbH
C. R. Bard, Inc.
Caladrius Biosciences, Inc.
Cellerant Therapeutics, Inc.
Cryolife Inc.
Cytograft Tissue Engineering, Inc.
Cytori Therapeutics, Inc.
Episkin
Gamida Cell Ltd.
Histogenics Corporation
Integra Lifesciences Holdings Corporation
International Stem Cell Corporation
Japan Tissue Engineering Co Ltd
Koninklijke DSM NV
Lifecord International Co Ltd
Ocata Therapeutics, Inc
Organogenesis Inc.
Osiris Therapeutics, Inc.
Piramal Enterprises Limited
RTI Surgical, Inc.
Stemcell Technologies Inc.
Taxus Cardium Pharmaceuticals Group, Inc.
TETEC? Tissue Engineering Technologies AG
Tissue Regenix Group PLC
Viacyte, Inc.
Zimmer Biomet Holdings Inc.