Advancements of novel therapies in the fields of tissue engineering and regenerative medicine have opened up new avenues for addressing a range of major diseases such as cancer; skin; cardiovascular conditions; urology; dental; neurological disorders including Alzheimer´s and Parkinson´s; and other. Engineered tissues can be successfully constructed through the recreation of a biologically active extracellular environment in which the product can be developed. These technologies offer new hope for medical progress, and the economies of emerging nations have recognized the potential of tapping into these fast emerging fields to gain maximum mileage.
The global market for the therapeutic areas of Tissue Engineering analyzed in this study comprises Orthopedics, Integumentary, Oncology, Cardiology, Dental, Neurology and Other. Individual regions analyzed in the study includes the United States, Europe, Asia-Pacific and Rest of World. Estimated to value US$11 billion in 2012, the global market for tissue engineering is expected to touch US$27 billion by 2018.
This 153 page global market report includes 27 rich data tables, supported with meaningful and easy to understand graphical presentation, of market numbers. The statistical tables represent the data for the global market value by geographic regions and application areas.
The report covers the brief business profiles of 60 major players across the United States - 47; Europe - 10; Asia-Pacific - 2; and Rest of World - 1. The report also provides the listing of the companies engaged in the business related to Tissue Engineering. The global list covers the addresses, contact numbers and the website addresses of 364 companies.
1. INTRODUCTION
2. PRODUCT OUTLINE
2.1 Biomaterials
2.2 Cells
2.3 Biomolecules
2.4 Aspects of Engineering Design
2.5 Biomechanical Design Aspects
2.6 Informatics to Support Tissue Engineering
2.7 Stem Cell Research
2.8 Therapeutic Applications of Tissue Engineering and Regenerative Medicine
2.8.1 Orthopedic Applications
2.8.1.1 Bone Regeneration Using Orthopedic Tissue Engineering
2.8.1.2 Articular Cartilage Degeneration and Osteoarthritis, Repair, Regeneration and Transplantation
2.8.1.2.1 Cartilage Repair
2.8.1.2.2 Osteochondral Allograft Transplantation
2.8.2 Skin/Integumentary Applications
2.8.2.1 Burns
2.8.2.2 Diabetic Ulcers
2.8.2.3 Venous Ulcers
2.8.2.4 Plastic and Reconstructive Surgery
2.8.3 Oncology Applications
2.8.3.1 Cancer
2.8.3.2 Cancer Biology from Tissue Engineering´s Perspective
2.8.3.3 Tissue Engineering Technology Platforms´ Translation into Cancer Research
2.8.4 Cardiovascular Applications
2.8.4.1 Cardiac Tissue Engineering: An Overview
2.8.4.2 Identification of Basic Cell Responses
2.8.4.2.1 Materials and Degradation
2.8.4.2.2 Attachment
2.8.4.2.3 Stiffness
2.8.4.2.4 Diffusion and Porosity
2.8.4.2.5 Forces
2.8.4.3 3-Dimensional Tissue Engineering
2.8.4.4 Further 3-D Approaches and Considerations
2.8.4.5 Cardiovascular Tissue Engineering and Bioreactor Technology
2.8.4.6 Limiting Cells or Materials
2.8.5 Dental
2.8.5.1 Dental Tissue Regeneration through Tissue Engineering Strategy
2.8.5.2 Harvesting Teeth Created by Tissue Engineering
2.8.5.3 Research Goals Currently Targeted
2.8.5.4 Process of Tissue Engineering for Tooth Replacement: What Future Trends Indicate
2.8.6 Neurology Applications
2.8.6.1 Neural Tissue Engineering or Neuroregeneration
2.8.6.2 Biomaterial Scaffold Development for Nerve Tissue Engineering: Biomaterial Mediated Neural Regeneration
2.8.6.2.1 Response to Injury and Repair
2.8.6.2.2 Neural Cells´ Regeneration Potential
2.8.6.2.3 Regeneration Promoted through Growth Factor Delivery
2.8.6.2.4 Biomaterials in Nerve Regeneration
2.8.6.2.5 Polymeric Scaffolds as Extracellular Matrix Analogues
2.8.6.2.6 Geometric Indicators: Structure of Scaffolds
2.8.6.2.7 Nanofiber Properties and Electrospinning Technology
2.8.6.2.8 Alternate Approaches
2.8.6.2.9 Electrical Cues
2.8.7 Urological Applications
2.8.7.1 Conditions Affecting the Urological System
2.8.7.1.1 The Kidney
2.8.7.1.2 The Ureter
2.8.7.1.3 The Urinary Bladder
2.8.7.1.4 The Urinary Sphincters
2.8.7.1.5 The Urethra
2.8.7.2 Stem Cells Offering Promise in Urological Regenerative Medicine
2.8.7.3 Polymeric Materials and their Potential Applications in Urologic Regenerative Medicine
2.8.8 Organ Transplantation
2.8.8.1 Categories of Transplant
2.8.8.2 Major Organs and Tissues Transplanted
3. KEY MARKET TRENDS
What Lies in Store for Cartilage Regeneration Stem Cells
Improved Scaffold for Bone Tissue Engineering Developed by Iranian Researchers
Magnetic Levitation for Bio-Assembling in 3-D
UK´s Footing in Regenerative Medicine Gaining Pace
Chondrogenesis and Cartilage Tissue Engineering: The Way Ahead
Regenerative Medicine Evolving, though Investors Still Wary
Scientific Innovation Announced by LifeNet Health´s Institute of Regenerative Medicine
Skin Stem Cells to Cure Genetic Liver Disease
Future Markets for Tissue Engineering and Cell Therapy
Timescale for Development
Tissue Engineering and Ultrasound Technologies
Overview of Myocardial Tissue Engineering (MTE)
Future of Bone Regeneration and Organ Printing
New Tissue Engineering Technology on the Way for Patients with Osteoarthritis
Leg Muscle Regenerated from Pig Bladder Cells
Loading Device for Intervertebral Disc Tissue Engineering
Rodent Spine Biomechanical Function Restored with Tissue-Engineered Intervertebral Discs
Engineering Human Tissue Regeneration via Novel Method
Heart Tissue Healing Assisted by New Nanotechnology
Developing Bioengineered Veins with Tissue Engineered Vascular Grafts a Promising Prospect
New Organs, New Hope for Children Offered by Regenerative Medicine
TERM: A Consortium Formed by Eight European Regions to Focus on Bolstering Tissue Engineering and Regenerative Medicine Initiatives
An Overview of Dental Pulp Tissue Engineering
Bioactive Electrospun Scaffolds to Deliver Growth Factors and Genes for Tissue Engineering Applications
Regenerative Medicine: Progress and Prospects
"Bio-Legos": An Innovation in Tissue Engineering
Pioneering Tissue-Engineered Urethras Report Success
4. MAJOR MARKET PLAYERS
5. KEY BUSINESS TRENDS
NeoStem Completes Amorcyte Acquisition
British Stem Cell Center Given the Go Ahead
Aragon Surgical, Inc Taken Over by Aesculap
Cellectis Acquires Cellartis
Advanced BioHealing, Inc Acquired by Shire plc
ProChon BioTech Acquired by Histogenics
Integra LifeSciences Takes Over SeaSpine
Stryker Acquires Orthovita
Medtronic´s Minority Stake in Tengion with a Focus on Regenerative Medicine Market
Cardiogenesis Acquired by CryoLife
Trial for Stem Cell-Based Therapy for IBD Commenced by Athersys-Pfizer
BioTime Acquires Glycosan BioSystems
Two Innovative Technologies Acquired by Boston Scientific
Allograft Cancellous Sponge Introduced by Integra LifeSciences
Eli Lilly in Partnership with the Juvenile Diabetes Research Foundation
Cell Targeting, Inc Acquired by BioTime
Boston Scientific Acquires Atritech
Intelect Medical Taken Over by Boston Scientific
Progenitor Cell Therapy Taken Over by NeoStem
Avid Radiopharmaceuticals Taken Over by Eli Lilly
Integra™ Endoscopic Gastroc Release System (EGR) Launched by Integra LifeSciences
Integra LifeSciences Launches New Range of Surgical Spine Instruments
Lilly Acquires Alnara Pharmaceuticals
Celgene Acquires Abraxis BioScience Inc
First Regenerative Medicine Product from Harvard Bioscience
Novel Bioactive Scaffold from Drexel
6. GLOBAL MARKET OVERVIEW
6.1 Global Market Analysis by Therapeutic Area
Chart 1: Global Tissue Engineering Market Analysis (2008-2018) by Therapeutic Area – Orthopedics, Integumentary, Oncology, Cardiology, Dental, Neurology and Other in USD Million
Chart 2: Glance at 2008, 2013 and 2018 Global Tissue Engineering Market Share (%) by Therapeutic Area – Orthopedics, Integumentary, Oncology, Cardiology, Dental, Neurology and Other
6.2 Tissue Engineering Therapeutic Area Analysis by Global Region
6.2.1 Orthopedics
Chart 3: Global Market Analysis of Tissue Engineering in Orthopedic Applications (2008-2018) by Geographic Region – United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 4: Glance at 2008, 2013 and 2018 Global Market Share (%) of Tissue Engineering in Orthopedic Applications by Geographic Region – United States, Europe, Asia-Pacific and Rest of World
6.2.2 Integumentary
Chart 5: Global Market Analysis of Tissue Engineering in Integumentary Applications (2008-2018) by Geographic Region – United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 6: Glance at 2008, 2013 and 2018 Global Market Share (%) of Tissue Engineering in Integumentary Applications by Geographic Region – United States, Europe, Asia-Pacific and Rest of World
6.2.3 Oncology
Chart 7: Global Market Analysis of Tissue Engineering in Oncology Applications (2008-2018) by Geographic Region – United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 8: Glance at 2008, 2013 and 2018 Global Market Share (%) of Tissue Engineering in Oncology Applications by Geographic Region – United States, Europe, Asia-Pacific and Rest of World
6.2.4 Cardiology
Chart 9: Global Market Analysis of Tissue Engineering in Cardiology Applications (2008-2018) by Geographic Region – United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 10: Glance at 2008, 2013 and 2018 Global Market Share (%) of Tissue Engineering in Cardiology Applications by Geographic Region – United States, Europe, Asia-Pacific and Rest of World
6.2.5 Dental
Chart 11: Global Market Analysis of Tissue Engineering in Dental Applications (2008-2018) by Geographic Region – United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 12: Glance at 2008, 2013 and 2018 Global Market Share (%) of Tissue Engineering in Dental Applications by Geographic Region – United States, Europe, Asia-Pacific and Rest of World
6.2.6 Neurology
Chart 13: Global Market Analysis of Tissue Engineering in Neurology Applications (2008-2018) by Geographic Region – United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 14: Glance at 2008, 2013 and 2018 Global Market Share (%) of Tissue Engineering in Neurology Applications by Geographic Region – United States, Europe, Asia-Pacific and Rest of World
6.2.7 Other Therapeutic Areas
Chart 15: Global Market Analysis of Tissue Engineering in Other Therapeutic Applications (2008-2018) by Geographic Region – United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 16: Glance at 2008, 2013 and 2018 Global Market Share (%) of Tissue Engineering in Other Therapeutic Applications by Geographic Region – United States, Europe, Asia-Pacific and Rest of World
7. REGIONAL MARKET OVERVIEW
Chart 17: The Projection of Key Market Region in terms of Growth for Tissue Engineering by Geography – Asia-Pacific, South America, Europe and North America
Chart 18: Global Tissue Engineering Market Analysis (2008-2018) by Geographic Region – United States, Europe, Asia-Pacific and Rest of World in USD Million
Chart 19: Glance at 2008, 2013 and 2018 Global Tissue Engineering Market Share (%) by Geographic Region – United States, Europe, Asia-Pacific and Rest of World
7.1 THE UNITED STATES
Chart 20: United States Tissue Engineering Market Analysis (2008-2018) by Therapeutic Area – Orthopedics, Integumentary, Oncology, Cardiology, Dental, Neurology and Other in USD Million
Chart 21: Glance at 2008, 2013 and 2018 United States Tissue Engineering Market Share (%) by Therapeutic Area – Orthopedics, Integumentary, Oncology, Cardiology, Dental, Neurology and Other
7.2 EUROPE
Chart 22: Western Europe Tissue Engineering Market Analysis (2008-2018) by Therapeutic Area – Orthopedics, Integumentary, Oncology, Cardiology, Dental, Neurology and Other in USD Million
Chart 23: Glance at 2008, 2013 and 2018 Western Europe Tissue Engineering Market Share (%) by Therapeutic Area – Orthopedics, Integumentary, Oncology, Cardiology, Dental, Neurology and Other
7.3 ASIA-PACIFIC
Chart 24: Asia-Pacific Tissue Engineering Market Analysis (2008-2018) by Therapeutic Area – Orthopedics, Integumentary, Oncology, Cardiology, Dental, Neurology and Other in USD Million
Chart 25: Glance at 2008, 2013 and 2018 Asia-Pacific Tissue Engineering Market Share (%) by Therapeutic Area – Orthopedics, Integumentary, Oncology, Cardiology, Dental, Neurology and Other
7.4 REST OF WORLD
Chart 26: Rest of World Tissue Engineering Market Analysis (2008-2018) by Therapeutic Area – Orthopedics, Integumentary, Oncology, Cardiology, Dental, Neurology and Other in USD Million
Chart 27: Glance at 2008, 2013 and 2018 Rest of World Tissue Engineering Market Share (%) by Therapeutic Area – Orthopedics, Integumentary, Oncology, Cardiology, Dental, Neurology and Other
8. GUIDE TO THE INDUSTRY
8.1 North America
8.1.1 Canada
8.1.2 United States
8.2 Europe
8.2.1 Belgium
8.2.2 Cyprus
8.2.3 Denmark
8.2.4 Finland
8.2.5 France
8.2.6 Germany
8.2.7 Iceland
8.2.8 Ireland
8.2.9 Italy
8.2.10 Luxembourg
8.2.11 Spain
8.2.12 Sweden
8.2.13 Switzerland
8.2.14 The Netherlands
8.2.15 Turkey
8.2.16 United Kingdom
8.3 Asia-Pacific
8.3.1 Australia
8.3.2 China
8.3.3 Hong Kong
8.3.4 India
8.3.5 Japan
8.3.6 Malaysia
8.3.7 New Zealand
8.3.8 Singapore
8.3.9 South Korea
8.4 Rest of World
8.4.1 Argentina
8.4.2 Israel
9. ANNEXURE
9.1 Research Methodology
9.2 The Questionnaire
9.3 Feedback
Advanced Cell Technology Inc
Aesculap/B. Braun
Athersys Inc
Baxter International Inc
Bayer Healthcare Pharmaceuticals
Biocomposites Ltd
Biolife Solutions Inc
Biomet Inc
Biotissue Technologies GmbH
Cardium Therapeutics
Celgene Corporation
Cellerant Therapeutics Inc
Corcell Companies, Inc
Cryobanks International Inc
Cryo-Cell International, Inc
Cryolife, Inc
Cryo-Save Group N.V.
Cytori Therapeutics Inc
Depuy
Eli Lilly and Co
ES Cell International Pte Ltd
Gamida Cell Ltd
Genta, Inc
Genzyme Biosurgery Corp
Genzyme Corp
Geron Corporation
Glaxosmithkline Plc
Histogenics Corp
Incytu Inc
Integra Lifesciences Inc
International Stem Cell Corporation
Johnson & Johnson Inc
Kensey Nash
Kinetic Concepts, Inc.
Lifecell Corp
Lifecord International Co Ltd
Medtronic Sofamor Danek Inc
Neostem, Inc.
Novartis Ag
Novo Nordisk A/S
Organogenesis Inc.
OSI Pharmaceuticals Inc
Osiris Therapeutics Inc.
Osteotech, Inc.
Pfizer Inc
Regenerative Sciences Institute
RTI Biologics, Inc
Sanofi-Aventis
Smith & Nephew Ltd
Stryker Corporation
Synovis Life Technologies, Inc
Synovis Orthopedic and Woundcare, Inc
Tengion, Inc
Thermogenesis Corp
Tissue Engineering, Inc.
Tissue Repair Company
Viacord
Viacyte, Inc.
W.L. Gore & Associates
Zimmer Holdings Inc
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